Searchable abstracts of presentations at key conferences in endocrinology

ea0092ps1-08-02 | Translational 1 | ETA2023

Transcriptomic analysis reveals tumor microenvironment plays important role in nodal metastasis of papillary microcarcinomas

Kim Mijin , Ryang Soree , Kim Seong-Jang , Hwa Kwon Chae , Hyun Kim Bo

Objectives: Attempts have been made to identify markers for aggressive disease in papillary microcarcinomas (PMCs), but genetic alterations identified in PMCs have failed to distinguish tumors with high-risk features. Thus, we aimed to identify candidate markers associated with lateral node metastasis (N1b) in patients with PMC through a transcriptomic analysis.Methods: Bulk RNA sequencing was performed in 26 matched tumor and normal thyroid tissue sampl...